Hepatitis C Virus: From Molecular Virology to Antiviral Therapy by Ralf Bartensc

Description: Hepatitis C Virus: From Molecular Virology to Antiviral Therapy by Ralf Bartenschlager Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted. Back Cover Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted. Table of Contents The Origin of Hepatitis C Virus.- Cell Culture Systems for Hepatitis C Virus.- Animal Models for Hepatitis C.- Hepatitis C Virus Entry.- Hepatitis C Virus Proteins: From Structure to Function.- Hepatitis C Virus RNA Translation.- Hepatitis C Virus RNA Replication.- Virion Assembly and Release.- Innate Immune Responses to Hepatitis C Virus.- Adaptive Immune Responses in Hepatitis C Virus Infection.- Liver Injury and Disease Pathogenesis in Chronic Hepatitis C.- Hepatitis C Virus-Specific Directly Acting Antiviral Drugs.- Treatment of Chronic Hepatitis C: Current and Future. Feature A comprehensive review Written by leading experts Richly illustrated Details ISBN3642273394 Author Ralf Bartenschlager Year 2013 ISBN-10 3642273394 ISBN-13 9783642273391 Media Book Format Hardcover Short Title HEPATITIS C VIRUS FROM MOLECUL Edition Description 2013 Language English Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. K Place of Publication Berlin Country of Publication Germany Edited by Ralf Bartenschlager DEWEY 616.3623 Pages 346 Edition 2013th Subtitle From Molecular Virology to Antiviral Therapy DOI 10.1007/978-3-642-27340-7 Illustrations 20 Illustrations, color; 14 Illustrations, black and white; VIII, 346 p. 34 illus., 20 illus. in color. Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Series Current Topics in Microbiology and Immunology Publication Date 2013-03-15 Alternative 9783642429361 Series Number 369 Audience Professional & Vocational We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96371715;

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